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Description:

Aim

- To outline the Chinese 7-ACA industry from aspects of production, import & export.
- To summarize & introduce the Chinese 7-ACA manufacturers
- To introduce the research situation on the above intermediates in China
- To evaluate the competitiveness of Chinese 7-ACA industry
- To summarize the cephalosporin industry in brief

Scope

This project mainly researches 7-ACA along the value chain, including
• Lactams
• Penicillins
• Cephalosporins
• Cefazolin sodium
• Cefoperazone sodium
• Cefotaxime sodium
• Ceftriaxone sodium

Highlights

China started researching on 7-ACA in 1980s, but China had not grasped the production technology until 1999. During that period, a vast amount of capital had been spent on the imported product. These years, China has made great achievement in bulk cephalosporin pharmaceuticals. The short supply of 7-ACA has become the bottleneck for the further development of cephalosporin industry.

In general, China's production of 7-ACA has been weak in the past few years. As a result, China had to spend a lot of money importing 7-ACA from Korea, Italy, Austria, etc. The total output of 7-ACA was only 400 tonnes in 2001, which failed to meet the domestic demand. Since 2002, some large producers planned to increase their production capacity of 7-ACA.

In recent years Chinese 7-ACA industry developed fast, and there are 5 active producers of 7-ACA in China. In 2001, the self-sufficiency rate was only about 20%, but in 2003 it reached 80% and about 15% of homemade 7-ACA was exported. Chinese 7-ACA has become strong and can compete with overseas ones.

In the past years, Chinese manufacturers has successfully exported their 7-ACA to India. There is no doubt that Chinese 7-ACA will occupy more market share in the future. Chinese competitiveness has been enhanced and will be enhanced in the future.

Main Content:

I. Production & Market Information
Executive Summary
Introduction
Methodology & Sources
Glossary
Brief Introduction to the Situation of b-Lactams, Penicillins and Cephalosporins in China
About b-Lactams
About Penicillins
Overall View on Production and Commercial Situation of Penicillins in China
About Cephalosporins
I. Production & Market Information
I-1 Brief Introduction to Cephalosporins in China
Problems of Beta lactams Industry in China
I-2 Production of 7-ACA in the Past Few Years
3 Price in Recent Years
I-3 Import & Export Analysis of 7-ACA in 2001, 2002 and First Half 2003
I-3.1 Import & Export Situation of 7-ACA in 2002
5.2.1 Import Situation – Breakdown by Origin
5.2.2 Import Situation – Breakdown by Importers
5.2.3 Export Situation
I-3.2 Import & Export Analysis of 7-ACA in 2002 and First Half 2003
I-4 Brief Summary on Downstream Products of 7-ACA
I-4.1 Cefazolin sodium
I-4.2 Cefoperazone sodium
I-4.3 Cefotaxime sodium
I-4.4 Ceftriaxone sodium
Other Down Stream Products of 7-ACA in China
I-5 Information of Raw Materials for 7-ACA
I-6 Research Situation of 7-ACA in China
I-6.1Flowchart of 7-ACA Production
I-6.2 Production Method of 7-ACA
I-6.3 Active Researchers in China
I-7 Government Management on the Production of 7-ACA in China

II. Manufacturers of 7-ACA in China
II-1 Active 7-ACA Producers in China
II-1.1 Shijiazhuang Pharmaceutical Group Zhongrun Pharmaceutical Co., Ltd.
…………
II-1.5 Zhejiang Hisun Pharmaceutical Co., Ltd.
II-2 Potential Projects
II-2.1 Nanyang Pukang Group Fangyuan Pharmaceutical Co., Ltd.
Other Producers of Cephalosporins
Other Manufacturers That Were Reported to Produce the Intermediate
Conclusion & Recommendation
Other Information

LIST OF TABLES
Table 1. Production of b-Lactams 1996-1998 (Unit: Mt)
Table 2. Production percentage of b-Lactams among the antibiotics
Table 3. The production of penicillins during 1996-2003 (unit: Mt) EXCEL1
Table 4. Production of bulk cephalosporins during 1996-1998 (unit: Mt) EXCEL 2
Table I-1-1 Production of cephalosporins (bulk material) in 1999 and 2002 (Unit: MT)
Table 1994-1999 HPDIS Cephalosporin quantity (DDDs/inhabitant x year), proportion % and growth rate %
Table I-2-1 Summary of 7-ACA in China
Table I-3-1 The import & export of 7-ACA & 7-ADCA in the past years
Table I-3-2 Import & Export of 7-ACA and 7-ADCA in 2001
Table I-3-3 Import & Export of 7-ACA in 2001 and 2002
Table I-3-4 Import and Export situation of 6-APA, 7-ADCA and 7-ACA in 2002
Table I-3-5 Import situation of cephalosporin antibiotic in January 2003
Table I-3-6 Import situation of these three producers
Table I-3-7 Export situation of these three producers
Table I-3.1-1 Importers of 7-ACA in 2001
Table I-3.2-1 Active exporter of 7-ACA in 2002 and first half 2003
Table I-3.2-2 Export destination of 7-ACA in 2002 and first half 2003
Table I-3.2-3 Export port of 7-ACA in 2002 and first half 200
Table I-3.2-4 Origin of 7-ACA in 2002 and first half 2003
Table I-3.2-5 Import port of 7-ACA in 2002 and first half 2003
Table I-3.2-6 Active importers of 7-ACA in 2002
Table I-3.2-7 Active importers of 7-ACA in first half 2003
Table I-4-1 Production situation of major downstream products of 7-ACA
Table I-4.1-1 The production of cefazolin sodium in the past years (Unit: MT)
Table I-4.1-2 The import & export of cefazolin sodium in the past years
Table I-4.1-3 Manufacturers of cefazolin in China (Unit: MT)- year 2000
Table I-4.1-4 Manufacturers of cefazolin in China (Unit: MT)- year 2002
Table I-4.2-1 The production of cefoperazone in the past years (Unit: MT)
Table Manufacturers who have ability to produce cefoperazone in China. –year 2000
Table I-4.2-2 Manufacturers who have ability to produce cefoperazone in China–year 2002
Table I-4.2-3 The import & export of cefoperazone in the past years
Table I-4.3-1 The production of cefotaxime in the past years (Unit: MT)
Table Manufacturers of cefotaxime in China (Unit: MT)-year 2000
Table I-4.3-2 Manufacturers of cefotaxime in China (Unit: MT)-year 2002
Table I-4.3-3 The import & export of cefotaxime in the past years
Table I-4.4-1 The production of ceftriaxone in the past years (Unit: MT)
Table I-4.4-2 The import & export of ceftriazone in the past years
Table Manufacturers of ceftriaxone in China (Unit: MT)-year 2000
Table I-4.4-3 Manufacturers of ceftriaxone in China (Unit: MT)-year 2002
Table The active producers of CPC in China

LIST OF FIGURES
I-6.1 Flowchart of 7-ACA Production

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Executive Summary

(Note: The following summary is based on the situation in 2003 and maybe different to what it is nowadays. Please be noted.)

- The commercial production of 7-ACA in China started from 1999.

- There are xx manufacturers in China. xxxx is most active in both production and export.

- The total capacity of 7-ACA by 2002 is claimed to be xxx MTs/year.

- The production in 2001 & 2002 is claimed to be around xxxx MTs and xxxx MTs, respectively.

- The import quantity and export quantity in 2001 is xxxMT and xxxMT, respectively. While the import quantity and export quantity in 2002 is xxxx MTs and xxxx MTs, respectively.

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(The rest content of this report is omitted.)

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